An international team of scientists has discovered that carolactones inhibit the MTHFD1 gene, helping to prevent the corona virus from causing the Covid-19 pandemic.
According to SCMP, an international team of scientists from China, Singapore and the United States on March 30 announced the study of bat genes that are expected to boost the production of drugs for Covid- 19.
Specifically, the scientists said that carolactones, which help inhibit a specific gene in bats, could help prevent the spread of Sars-CoV-2 virus, the corona virus strain that causes Covid-19.
The international team of scientists studied the gene functions of the black-crested bat and discovered that carolactones inhibit the MTHFD1 gene. Remarkably, MTHFD1 is a key gene in the production of purine, an essential organic compound in the viral process of reproduction on both bats and humans.
Scientists believe that MTHFD1 may be a potential target for the development of anti-viral drugs in general and Sars-CoV-2 in particular. The host cells have a higher ability to inhibit MTHFD1 than the virus strains, opening up the opportunity for treatment with antiviral drugs, targeting the MTHFD1 gene.
“Inhibition of MTHFD1 can prevent the multiplication of multiple virus strains, including influenza, mumps virus, Melaka virus, and Zika virus,” the study said.
Scientists say developing an anti-virus drug specifically for Covid-19 is similar to developing anti-cancer drugs, because they all focus on the specific genes that cancer cells need to multiply.
Bats are considered to be the host of many viruses that cause human endemic diseases such as Ebolo, acute respiratory infection SARS, and now Covid-19. To date, the number of people infected with Covid-19 has exceeded 870,000 cases, including more than 43,000 deaths.